Early Watchlist: Entero Therapeutics (NASDAQ: ENTO) Tops Our Watchlist This Morning—Here’s Why

Market Crux Announces Its Next Exclusive Profile! Entero Therapeutics, Inc. (Nasdaq: ENTO) is Our Next Potential Breakout Idea and We’re Initiating Coverage For This Monday. Here’s What We Know About Entero Therapeutics, Inc. (Nasdaq: ENTO)—So Far: With fewer than 4.7M shares available, (ENTO) has seen sharp moves, including recent 60%, 72%, and 124% approx. swings. And with a market cap coming in at just $2.35M, even a minor breakthrough in its late-stage pipeline could make a big impact. Entero Therapeutics, Inc. (Nasdaq: ENTO) is developing three GI treatments, including a Phase 3-ready therapy for celiac disease. FDA Fast Track Designation and a Phase 3 trial expected in 2025 add  credibility to its pipeline. On Friday, (ENTO) closed above its 5-day moving average, with key resistance levels ahead that could trigger the potential for further moves. With no FDA-approved treatments for celiac disease and few options for gastroparesis and pancreatic insufficiency, Entero Therapeutics, Inc. (Nasdaq: ENTO) is addressing significant medical needs. Entero Therapeutics, Inc. (Nasdaq: ENTO) remains largely undiscovered—but history shows that companies like this don’t fly under the radar forever. March 3, 2025 Dear Reader, Our early watchlist is ready.  And Entero Therapeutics (NASDAQ: ENTO) is topping our radar this morning—keep reading to see why. In the world of biotech and pharma, it only takes one game-changing development to propel an overlooked company into mainstream attention. Last Monday morning, we saw it firsthand—our profile from last Sunday night surged approximately 94% shortly after the opening bell rang. And now, we’re keeping an eye on another name with similar characteristics. Enter Entero Therapeutics, Inc. (Nasdaq: ENTO). This late-stage clinical biopharmaceutical company is developing targeted, non-systemic therapies for serious gastrointestinal diseases, a space where countless patients continue to seek more effective treatment options. With multiple candidates in the pipeline, including a potential first-in-class oral therapy for celiac disease, Entero Therapeutics, Inc. (Nasdaq: ENTO) has positioned itself in a high-growth sector. But what really makes this one interesting? Why Entero Therapeutics, Inc. (Nasdaq: ENTO) is Topping Our Watchlist Tomorrow. With less than 4.7M shares in the float, (ENTO) has the kind of low-float structure that has the potential to move quickly if demand begins to shifts Just look at these recent moves: Approx. 60% overnight move 12/04/2024: $0.4600 → 12/05/2024: $0.7400 Approx. 72% overnight move 12/05/2024: $0.4800 → 12/06/2024: $0.8300 Approx. 124% move in under two weeks 11/27/2024: $0.4124 → 12/09/2024: $0.9260 Pair that with a tiny $2.35M market cap, and it’s clear that even a small breakthrough in their pipeline could have a big impact. Technical Indicators Show Signs of Momentum Beyond the fundamentals, Entero Therapeutics, Inc. (Nasdaq: ENTO) is also showing technical strength. Recently closed above its 5-day moving average—a short-term bullish signal that often attracts momentum traders. Key resistance levels at the 20, 50, 100, and 200-day moving averages—if broken, these could fuel further upside potential. Low float + bullish technical signals = a combination that’s caught attention before. For now, this name remains under the radar. But as history has shown—companies like this don’t stay quiet forever.) Entero Therapeutics, Inc. (Nasdaq: ENTO) is a clinical-stage biopharmaceutical company dedicated to developing targeted, non-systemic therapies for serious gastrointestinal (GI) diseases, where current treatment options remain limited. Formed through the merger of First Wave BioPharma and ImmunogenX, Entero Therapeutics, Inc. (Nasdaq: ENTO) has built a robust pipeline of late-stage clinical assets aimed at addressing significant unmet medical needs in high-value healthcare markets. Advancing a Late-Stage Pipeline in GI Health Entero Therapeutics, Inc. (Nasdaq: ENTO) is focused on three key candidates, each with the potential to redefine treatment standards for major GI conditions: Latiglutenase (Phase 3 – Celiac Disease): A first-in-class oral biotherapeutic designed to help gluten-sensitive patients by improving gluten digestion and reducing symptoms. With no FDA-approved therapies for celiac disease, Latiglutenase could be a breakthrough solution for a vast population in need of better treatment options. Capeserod (Phase 2 – Gastroparesis & GI Disorders): Originally developed by Sanofi, this 5-HT4 receptor partial agonist is being repurposed to improve gastric motility in patients with gastroparesis and other GI disorders, conditions often underserved by current treatments. Adrulipase (Phase 2 – Exocrine Pancreatic Insufficiency - EPI): A recombinant lipase enzyme designed to enhance nutrient absorption in patients with cystic fibrosis and chronic pancreatitis, offering a potentially more effective alternative to traditional pancreatic enzyme replacement therapies (PERT). Strategic Growth & Market Position With clinical trials advancing across multiple programs, Entero Therapeutics, Inc. (Nasdaq: ENTO)  is well-positioned to capitalize on high-growth GI markets. The company has already secured: ✅ Exclusive Sanofi partnership rights for Capeserod, which could unlock new treatment pathways for gastroparesis and related GI conditions. ✅ A strong intellectual property portfolio, securing long-term market exclusivity across its pipeline assets.  ✅ FDA Fast Track Designation & Phase 3 Readiness for Latiglutenase, with pivotal trials expected to begin in early 2025. 7 Reasons Why Entero Therapeutics, Inc. (Nasdaq: ENTO) is Topping Our Watchlist Tomorrow Morning… 1. Low Float with Big Swings: With a float of less than 4.7M shares, (ENTO) has shown the ability to move quickly, including recent 60%, 72%, and 124% approx. swings in short time frames. 2. Tiny Market Cap, Room to Grow: At just $2.35M, even a small breakthrough in the company’s late-stage pipeline could have a significant impact. 3. Advancing a High-Potential Pipeline: The company is developing three late-stage GI treatments, including a Phase 3-ready oral therapy for celiac disease, a Phase 2 candidate for gastroparesis, and a Phase 2 enzyme therapy for exocrine pancreatic insufficiency. 4. Key Regulatory Milestones Secured: ENTO has FDA Fast Track Designation for Latiglutenase, a Phase 3 trial expected to begin in 2025, and a Sanofi-backed GI treatment moving into Phase 2 studies. 5. Technical Indicators Showing Momentum: ENTO has recently closed above its 5-day moving average, a short-term signal traders watch closely, with key resistance levels at the 20, 50, 100, and 200-day averages that could lead to further movement. 6. Addressing Unmet Needs in GI Health: With no FDA-approved treatments for celiac disease and limited options for gastroparesis and pancreatic insufficiency, ENTO is targeting high-demand medical conditions that could attract significant attention. 7. Still Under the Radar—for Now: Despite low float, bullish technicals, and a promising pipeline, ENTO remains relatively undiscovered—but history shows that companies like this don’t stay quiet forever. Consider Adding Entero Therapeutics (Nasdaq: ENTO) to Your Radar This Week… When it comes to low-float biotech names with a shot at something bigger, Entero Therapeutics (Nasdaq: ENTO) checks a lot of boxes. A tiny $2.35M market cap, a late-stage pipeline targeting high-demand GI conditions, and regulatory milestones already in place—it’s the kind of setup that tends to get noticed fast. Add in recent price swings of approx. 60%, 72%, and 124%, bullish technical indicators flashing, and a market that still hasn’t fully caught on?  When names like this start moving, they don’t stay quiet for long. We are locked in on (ENTO) this morning—consider taking a look while it’s still early.  Also, keep an eye out for my next update—it should be out very shortly. Sincerely, Gary Silver Managing Editor, MarketCrux MarketCrux.com (“MarketCrux” or “MC” ) is owned by Headline Media LLC, a multi member limited liability company. Data is provided from third-party sources and MarketCrux is not responsible for its accuracy. Make sure to always do your own research and due diligence on any day and swing profile MC brings to your attention. Any emojis used do not have a specific defined meaning, and may be used inconsistently. We do not provide personalized in.vest.ment advice, are not in.vest.ment advisors, and any profiles we mention are not suitable for all in.vest.ors. The owners of Headline Media LLC own and operate marketcrux . com (“MC”). From time to time, MC will publicly disseminate information about a company via website, email, SMS and other points of media. Please see important disclosure information here: marketcrux.com/disclaimer/ *Headline Media LLC has not been compensated for the March 2nd and 3rd, 2025's profile on (ENTO:US). Neither Headline Media LLC, TD Media LLC and their members own shares of (ENTO:US).

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