| Market Crux Announces Kairos Pharma, Ltd. (NYSE: KAPA) as Its New Exclusive Profile!
Kairos Pharma, Ltd. (NYSE: KAPA) Comes Backed by Several Potential Catalysts Including:
Recent IPO: Kairos Pharma, Ltd. (NYSE: KAPA) recently had its IPO, quietly entering the market and flying under Wall Street’s radar, until now.
Razor Thin Float: Less than 3.5M shares available to the public, creating potential for significant volatility with small shifts in demand.
Under Wall Street’s Radar: As a nano-cap with a market cap under $29M, Kairos Pharma, Ltd. (NYSE: KAPA) holds high growth potential typically seen in smaller companies.
Cutting-Edge Cancer Therapies: Developing novel treatments for aggressive cancers like prostate, lung, and glioblastoma, focusing on overcoming immune suppression and dr-ug resistance.
Diverse and Robust dr-ug Pipeline: Seven therapeutic candidates ranging from small molecules to biologics, reducing risks and maximizing impact on high-need cancer treatments.
Strong Partnership with Cedars-Sinai: Licensed technologies from Cedars-Sinai Medical Center, enhancing research capabilities and credibility, key to advancing clinical trials.
Addressing Unmet Needs in Cancer Treatment: ENV 105 targets cancers resistant to hormone and EGFR therapies, with promising early trial results for patients with limited options.
High-Growth Market Segments: Targeting multi-bill-ion-dollar cancer markets, including prostate, lung, and glioblastoma.
Make Sure Kairos Pharma, Ltd. (NYSE: KAPA) is at the Top of Your Watchlist Tomorrow Morning.
September 23, 2024
Dear Reader,
Drop everything and take a quick look at these 3 reasons why you should have Kairos Pharma, Ltd. (NYSE: KAPA) on your watchlist early tomorrow morning.
1. Recent IPO: Kairos Pharma, Ltd. (NYSE: KAPA) quietly had its IPO last week, entering the market with little fanfare. However, its strong focus on cutting-edge cancer therapies makes it one company to keep an eye on.
2. Razor Thin Float: With less than 3.5M shares available for the public, Kairos Pharma, Ltd. (NYSE: KAPA) has the potential for significant volatility, as even small shifts in demand could lead to big swings. 3. Higher Potential for Growth: As a nano-cap company with a market cap under $29M, Kairos Pharma, Ltd. (NYSE: KAPA) offers a higher potential for growth, a feature often seen in smaller companies that have room to expand dramatically compared to larger firms.
Keep reading to see what we discovered about Kairos Pharma, Ltd. (NYSE: KAPA) and why you should take a look at the company.
Few sectors in the market present such explosive potential as the biotech and biopharmaceutical space, where companies can go from relatively unknown to industry giants on the back of a single breakthrough.
This is especially true when a company shows promise in addressing some of the biggest challenges in healthcare.
Biotechs hit a two-year high this summer on a wave of promising clinical news, as Wall Street seemed to return to the biotech universe in late 2023 and early 2024 when Big Pharma began putting its dry powder to work on takeovers.
Last week, however, Kairos Pharma, Ltd. (NYSE: KAPA) quietly had its IPO, flying under the radar of many on Wall Street—until now.
But one thing about Kairos Pharma, Ltd. (NYSE: KAPA) that has us excited is that there's less than 3.5M shares available in the public float.
With this type of share structure, Kairos Pharma, Ltd. (NYSE: KAPA) has the potential for big swings and volatility if demand begins to shift. | |  | | Kairos Pharma, Ltd. (NYSE: KAPA) is also considered a nano-cap. In general, nano-cap companies have market capitalizations of less than $50M.
Because nano-caps are significantly smaller than mid cap or large cap companies, they have a higher potential for growth.
As of Friday, 9/20/2024, Kairos Pharma, Ltd. (NYSE: KAPA) has a market cap of less than $29M (approx.) according to FinViz.
Kairos Pharma, Ltd. (NYSE: KAPA) is a little-known, clinical-stage biopharmaceutical company that stands at the cutting edge of cancer therapeutics.
Focused on the development of novel treatments for some of the most aggressive and treatment-resistant cancers, Kairos Pharma, Ltd. (NYSE: KAPA)’s mission is to overcome critical barriers in cancer therapy, particularly immune suppression and dr-ug resistance.
Leveraging innovative science and breakthrough technologies, the company is pioneering a new class of antibodies and small molecules aimed at transforming the treatment landscape for cancers such as prostate, lung, breast cancer, and glioblastoma.
A Comprehensive and Diversified Portfolio
Kairos Pharma, Ltd. (NYSE: KAPA)’s strength lies in its diversified portfolio of seven therapeutic candidates, each designed to tackle different cancer types and mechanisms of resistance.
This approach mitigates the risks commonly associated with biopharmaceutical development by spreading them across multiple avenues of research and clinical trials.
Among these seven candidates, five have been developed in-house by Kairos Pharma, Ltd. (NYSE: KAPA), while two are advanced-stage therapies brought in through the company’s acquisition of Enviro Therapeutics, Inc., a subsidiary dedicated to enhancing cancer treatment responses.
The company's proprietary technologies are licensed from the prestigious Cedars-Sinai Medical Center, the largest academic medical institution in the Western U.S., which is ranked number one in California and number two in the nation by U.S. News & World Report. | |  | | This partnership not only provides Kairos Pharma, Ltd. (NYSE: KAPA) with access to cutting-edge medical insights but also bolsters the company’s credibility and research capabilities.
Addressing the Core of Immune Suppression and dr-ug Resistance
One of the greatest challenges in cancer treatment is the ability of cancer cells to evade the immune system through immune checkpoints, which act as molecular switches that regulate immune responses.
Cancer cells often exploit these checkpoints, allowing them to grow unchecked by the body’s natural defenses.
Kairos Pharma, Ltd. (NYSE: KAPA)’s strategy is to develop small molecules and antibodies that specifically target these checkpoints, enabling the immune system to recognize and attack cancer cells more effectively.
At the forefront of this initiative is ENV 105, a biologic dr-ug designed to target the protein endoglin, which is upregulated in cancer cells and their surrounding microenvironment in response to treatments like androgen-targeted therapies and EGFR inhibitors.
By targeting both the cancerous cells and the surrounding support structures that help tumors thrive, ENV 105 offers a revolutionary approach to tackling dr-ug resistance.
ENV 105 is currently in a Phase 2 clinical trial for prostate cancer at Cedars-Sinai Medical Center.
In this trial, the dr-ug has shown a clinical benefit rate of 62%, stabilizing or shrinking tumors in patients who had developed resistance to widely used hormone therapies like enzalutamide and abiraterone.
Eyeing Market Potential
Kairos Pharma, Ltd. (NYSE: KAPA)’s focus on addressing unmet needs in the cancer treatment space positions it in a significant market.
The global prostate cancer therapeutics market was valued at $7.9B and is projected to grow rapidly, driven by the increasing prevalence of prostate cancer and the growing demand for advanced therapeutics.
ENV 105 is designed to serve patients who have developed resistance to standard androgen-targeted therapies, a population that continues to expand as more patients undergo hormone therapy for prostate cancer.
With nearly 1.2M new prostate cancer cases registered worldwide each year, the potential market for ENV 105 in combination with existing therapies could reach multi-billion-dollar levels.
ENV 105 is also being tested in a Phase 1 trial for non-small cell lung cancer (NSCLC), another area with vast market potential.
The global market for EGFR mutant non-small cell lung cancer was valued at $1.7B.
Lung cancer remains the leading cause of cancer-related deaths worldwide, and EGFR inhibitors like Tagrisso® (osimertinib) are currently the standard of care.
However, resistance to these therapies often develops, leaving a large unmet need for treatments like ENV 105 that can be used in combination with EGFR inhibitors to extend their efficacy.
Additionally, ENV 105 shows promise for application in other solid tumors, including head and neck cancers, which are projected to grow by 7.9% by 2030 due to increasing risk factors such as smo-king and alc-o-hol consumption.
The global head and neck cancer dr-ug market was valued at $1.51B in 2021, providing yet another possibility for ENV 105’s therapeutic potential.
T Cell Therapy for Glioblastoma
Another key candidate in Kairos Pharma, Ltd. (NYSE: KAPA)’s pipeline is KROS 201, a cutting-edge T cell therapy designed to target glioblastoma, one of the most deadly and aggressive forms of brain cancer.
Glioblastoma has proven exceptionally difficult to treat due to its rapid progression and high resistance to standard therapies like chemotherapy and radiation.
KROS 201 aims to tackle this challenge by harnessing the body’s own immune cells, specifically T cells, which are primed to attack cancer stem cells that fuel glioblastoma growth.
The global market for glioblastoma treatments is expected to grow significantly due to the lack of effective therapies, with the T cell therapy market projected to reach USD 20.8 billion by 2030, growing at a compound annual growth rate (CAGR) of 20.4% from 2022 to 2030.
KROS 201 has the potential to address this unmet need by offering a novel approach to glioblastoma treatment, targeting the cancer at its root through the activation of cytotoxic and helper T cells.
Expanding the Pipeline: Novel Immunotherapies |  | | Kairos Pharma, Ltd. (NYSE: KAPA)’s broad pipeline also includes KROS 101, a small molecule dr-ug targeting the GITR ligand, a checkpoint that regulates immune responses.
By stabilizing the GITR ligand, KROS 101 promotes the growth and activation of effector T cells while suppressing inhibitory T cells, enabling the immune system to mount a more potent attack on cancer cells.
The global immune checkpoint inhibitor market is estimated to grow from $31.4B to $148B by 2030, with Kairos Pharma, Ltd. (NYSE: KAPA) aiming to participate in this burgeoning market. |  | | Other exciting candidates include KROS 102, which is being developed as a GITR antagonist for autoimmune diseases, and KROS 401, a peptide-based therapy targeting tumor-associated macrophages (TAMs) in cancers like triple-negative breast cancer. The global peptide therapeutics market size was valued at $45.67B in 2023 and is expected to exceed $80.44B by 2033. The peptide therapeutics market growth is driven by an increasing prevalence of cancer and other metabolic diseases.
ENV 205: Overcoming Chemotherapy Resistance
Kairos Pharma, Ltd. (NYSE: KAPA)’s subsidiary, Enviro Therapeutics, Inc., is developing ENV 205, a first-of-its-kind biologic that targets mitochondrial DNA to address chemotherapy resistance in prostate cancer.
Chemotherapy resistance is a major hurdle in cancer treatment, especially in later stages, but by depleting mitochondrial DNA in circulation, ENV 205 aims to restore chemotherapy sensitivity and reduce the toxic side effects commonly associated with chemotherapy.
The global chemotherapy market is projected to reach $74.3B by 2027, providing Kairos Pharma, Ltd. (NYSE: KAPA) with a substantial market potential if ENV 205 proves successful.
Strategic Vision and Future Outlook | |  | | Kairos Pharma, Ltd. (NYSE: KAPA)’s strategy is built on advancing its multifaceted portfolio through clinical trials, with a focus on addressing the most pervasive challenges in cancer treatment: dr-ug resistance and immune suppression.
The company is aggressively pursuing strategic partnerships and collaborations with academic institutions like Cedars-Sinai, while also optimizing its pipeline to maximize commercial success.
Through its innovative therapies, deep molecular insights, and strategic partnerships, Kairos Pharma, Ltd. (NYSE: KAPA)’s aims to redefine cancer treatment and offer hope to patients with some of the most difficult-to-treat cancers.
By targeting not just the cancer cells but also the tumor’s microenvironment, Kairos Pharma, Ltd. (NYSE: KAPA) is addressing cancer at its most vulnerable points and creating possibilities for more effective, long-lasting treatments.
With a potential market size in the hundreds of bill-ions across its various dr-ug candidates, the company’s future holds significant promise both for its business growth and for the patients who stand to benefit from its innovative therapies.
7 reasons why Kairos Pharma, Ltd. (NYSE: KAPA) needs to be on your watchlist early this morning.
1. Razor Thing Float: With less than 3.5M shares available for the public, Kairos Pharma, Ltd. (NYSE: KAPA) has the potential for significant volatility, as even small shifts in demand could lead to big swings.
2. Under Wall Streets’ Radar: As a nano-cap company with a market cap under $29M, Kairos Pharma, Ltd. (NYSE: KAPA) offers a higher potential for growth, a feature often seen in smaller companies that have room to expand dramatically compared to larger firms.
3. Cutting-Edge Cancer Therapies: Kairos Pharma, Ltd. (NYSE: KAPA) is developing novel treatments aimed at overcoming key challenges in cancer treatment, including immune suppression and dr-ug resistance. With therapies designed for aggressive cancers like prostate, lung, and glioblastoma, the company is pioneering solutions where traditional treatments have failed.
4. Diverse and Robust dr-ug Pipeline: With seven therapeutic candidates in its portfolio—ranging from small molecules to biologics—Kairos Pharma, Ltd. (NYSE: KAPA) spreads its research across multiple avenues. This diversification reduces the risks inherent in dr-ug development and maximizes potential impact on several high-need cancer areas.
5. Strong Partnership with Cedars-Sinai: Kairos Pharma, Ltd. (NYSE: KAPA)’s technologies are licensed from Cedars-Sinai Medical Center, a top U.S. academic institution. This relationship provides the company with access to groundbreaking research, increasing its credibility and research capabilities, a key factor for advancing clinical trials and future approvals.
6. Addressing Unmet Needs in Cancer Treatment: ENV 105, one of Kairos Pharma, Ltd. (NYSE: KAPA)’s most advanced dr-ugs, targets cancers resistant to hormone therapies like prostate cancer and EGFR inhibitors in lung cancer. With promising results in early trials, ENV 105 could significantly improve outcomes for patients who have run out of treatment options.
7. High-Growth Market Segments: The cancers targeted by Kairos Pharma, Ltd. (NYSE: KAPA), including prostate, lung, glioblastoma, and others, represent several multi-bill-ion-dollar markets.
With its innovative therapies, Kairos Pharma, Ltd. (NYSE: KAPA) is aiming to make strides in these expanding sectors. - Prostate Cancer Therapeutics Market: Valued at $7.9B.
- EGFR Mutant Non-Small Cell Lung Cancer Market: Estimated at $1.7B.
- Glioblastoma Treatment Market: Projected to reach $20.8B by 2030.
- Chemotherapy Market: Projected to reach $74.3B by 2027.
- Immune Checkpoint Inhibitor Market: Estimated to grow from $31.4B to $148B by 2030.
- Peptide Therapeutics Market: Recently Valued at $45.67B, expected to exceed $80.44B by 2033.
| |  | | Last week, Kairos Pharma, Ltd. (NYSE: KAPA) quietly had its IPO, flying under the radar of many on Wall Street—until now. Despite its low-key debut, the company is already poised to make a significant impact in the field of cancer treatment.
With a diverse pipeline of seven innovative therapeutics, Kairos Pharma, Ltd. (NYSE: KAPA) is positioning itself to address critical challenges like immune suppression and dr-ug resistance in some of the most aggressive cancers, including prostate, lung, and glioblastoma.
Backed by a strong partnership with Cedars-Sinai Medical Center, Kairos Pharma, Ltd. (NYSE: KAPA)’s cutting-edge research gives it a competitive edge. With breakthrough therapies like ENV 105, which targets resistant prostate and lung cancers, and KROS 201, a novel T cell therapy for glioblastoma, the company is positioning itself to redefine cancer care.
As it focuses on high-growth markets and overcoming chemotherapy resistance, Kairos Pharma, Ltd. (NYSE: KAPA) is one little-known company that needs to be on your radar.
With less than 3.5M shares available in the public float, (KAPA) has the potential for volatility and big swings.
Pull up Kairos Pharma, Ltd. (NYSE: KAPA) and it to your watchlist early this morning.
I’m serious.
Take a good look at (KAPA) before the bell rings. I’ll check back in with you shortly. | | | Sincerely,
Gary Silver Managing Editor, MarketCrux | | MarketCrux (MarketCrux . com) is owned by Headline Media LLC, a limited liability company. Disclosure: I am not a lice.nsed finan.cial adviser. Make sure to always do your own research and due diligence on any day and swing profile I bring to your attention. MarketCrux full disclosure is to be read and fully understood before using MarketCrux website, or joining MarketCrux's email or text list. By viewing MarketCrux website and/or reading MarketCrux email or text newsletter you are agreeing to MarketCrux full disclosure which can be read at marketcrux.com/disclaimer Pursuant to an agreement between Headline Media LLC and TD Media LLC, Headline Media LLC has been hired for a period beginning on 09/22/2024 and ending on 09/23/2024 to publicly disseminate information about (KAPA:US) via digital communications. Headline Media LLC has been paid five thousand USD. We own zero shares of (KAPA:US). Please see important disclosure information here: https://marketcrux.com/kapa-disclosure-761/ | | | | |
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